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Florida Keys Commercial Real Estate for Sale in the Florida Keys

Commercial real estate in the Florida Keys is available everywhere from Key Largo to Key West.  These great pieces of property can include anything from a business to a store front to an office building for sale in the Keys.  For those living in or looking to relocate to the Florida Keys commercial real estate can provide a fantastic business opportunity in a community that thrives on tourism and industry.  Possibilities can include things such as restaurants, stores, and other small businesses.  For a complete set of Florida Keys MLS commercial listings, browse here.

Total Listings 141
Order By:

$2,500
Rockland Key
Calle Uno   - MM: 9.00
Bed, Baths, SqFt Days Listed: 1215
Industrial - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

$17,600
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 1,650 SqFt Days Listed: 1623
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$23,500
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 3,215 SqFt Days Listed: 1819
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$40,000
Key West
Old Town Unrecord   - MM: 1.00
Bed, Baths, 8,396 SqFt Days Listed: 2024
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$149,900
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 367 SqFt Days Listed: 341
-18.97% ($35,100) 5 Price Changes : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Very spacious office with skylight, located above the Courthouse Deli. Located in Old Town Key West just at the entrance of Truman Annex at the corner of Whitehead and Southard Street across from the Courthouse. The 367 Sq.ft. office is on the 3rd floor and building provides shared kitchenette and restrooms.

$195,000
Key Largo
Lake Surprise Properties   - MM: 106.00
Bed, Baths, 2,400 SqFt Days Listed: 264
Commercial - Active - Waterfront Yes
Side of Island: Bay/Gulf - n/a

2400 square feet ground floor currently leased to Deerfiled Trailer who sells, services and repairs trailers and other marine equiptment. Tenant has approximately 1000 square feet of unused space that can be sublet to another business. Building has Central Air.

$237,700
Key West
Key West Prof Plaza   - MM: 2.00
Bed, Baths, 2,337 SqFt Days Listed: 1212
-58.66% ($337,300) 4 Price Changes : Last Change 466 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Unique opportunity to own a office condo located on the 4th floor of the Kennedy Center. Unit 400 approximately 2337sq.ft., with an oversized top floor terrace overlooking Key Wests New Town area & canopy, shared with unit 402. Unit 400 is Bank Owned and is divided into 5 private offices w/ large bull-pen area, reception, storage, and kitchenette. Shared restroom facilities on each floor, also included in monthly condo dues: water, electric, bldg. maint. & insurance.

$250,000
Marathon
Olde Towne Centre   - MM: 52.50
Bed, Baths, 952 SqFt Days Listed: 41
-15.25% ($45,000) 2 Price Changes : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: Ocean - n/a

Opportunity awaits you in this unit. Directly across from the Marathon Airport and located off of US1 this unit is ready to have your personal vision applied to the space. With ample parking for clients/consumers this unit is sure to elevate your business to the next level. Adjoining Unit also offered for sale MLS#614922

$270,000
Marathon
First Professional   - MM: 50.00
Bed, Baths, 947 SqFt Days Listed: 312
-12.90% ($40,000) 4 Price Changes : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: Ocean - n/a

GREAT OPPORTUNITY TO OWN WELL ESTABLISHED BEAUTY SALON OR SPACE TO SUIT BUYERS NEEDS. PROFESSIONAL OFFICES ONLY ALLOWED BY CONDO RULES. Great Location near major shopping hub in Marathon. Currently set up for 3-4 hair stylists, 2 private rooms for massage or esthetician, and room for manicurists. There is a laundry closet including washer and dryer, a stock room and unisex restroom.

$275,000
Key West
Old Town Unrecord   - MM: 1.00
1 Bed, 1 Baths, SqFt Days Listed: 40
Misc Prop Rig - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

This is a transient license previously used for a Studio/1bed, 1bath unit. Buyer should verify transferability and conditions of transfer with the City of Key West Planning Department.

$275,000
Key West
Old Town Unrecord   - MM: 1.00
1 Bed, 1 Baths, SqFt Days Listed: 40
Misc Prop Rig - Active - Waterfront No
Side of Island: N/A - n/a

This is a transient license previously used for a Studio/1bed, 1 bath unit. Buyer should verify transferability and transfer conditions with the City of Key West Planning Department.

$275,000
Key West
Old Town Unrecord   - MM: 1.00
1 Bed, 1 Baths, SqFt Days Listed: 40
Misc Prop Rig - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

This is a transient license previously used for a studio/1 bed /1 bath located on South Street in Casa Marina. Sale of Transient license does not include a ROGO. .Buyer should verify transferability and conditions of transfer with the City of Key West Planning Department.

$275,000
Key West
Old Town Unrecord   - MM: 1.00
1 Bed, 1 Baths, SqFt Days Listed: 40
Misc Prop Rig - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

This is a transient license previously used studio/ 1 bed, 1 bath. Buyer should verify transferability and conditions of transfer with the City of Key West Planning Department.

$295,000
Marathon
Olde Towne Centre   - MM: 52.50
Bed, Baths, 952 SqFt Days Listed: 41
Commercial - Contingent - Waterfront No
Side of Island: Ocean - n/a

Welcome to 9705, this unit is ready for your personal touch. With ample parking, your clients/consumers are sure to appreciate this incredible location. Directly across from the Marathon Airport and direct off US1 this is all about location. Adjoining Unit also offered for sale MLS#614920.

$329,000
Key West
New Town Unrecord   - MM: 3.00
1 Bed, 1 Baths, 1,475 SqFt Days Listed: 1257
-17.54% ($70,000) 2 Price Changes : Last Change 883 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Office Condo for Sale, centrally located in New Town on the 3rd floor of the Kennedy Center. This Professional Building caters to a diversity of innovative businesses and entrepreneurs in a friendly business environment. Unit 303 is approximately 1475sq.ft. with 6 private offices, large conference room, oversized waiting room/ workspace, and kitchenette. This building offers adequate off-street parking, elevators, and public restrooms on each floor. Included in the monthly Assoc Dues: water, electric, building maint, building insurance.

$349,000
Key West
New Town Unrecord   - MM: 3.00
Bed, Baths, 2,058 SqFt Days Listed: 1257
-36.08% ($197,000) 3 Price Changes : Last Change 765 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Office Condo for Sale, centrally located in New Town on the 3rd floor of the Kennedy Center. This Professional Building caters to a diversity of innovative businesses and entrepreneurs in a friendly business environment. Unit 307/305B is approximately 2058sq.ft. with 2 entrances, open floor plan with many workspace options, kitchenette, full bathroom, waiting area, private balcony. This building offers adequate off-street parking, elevators, and public restrooms on each floor. Included in the monthly Assoc Dues: water, electric, building maint, building insurance.

$375,000
Big Coppitt
Porpoise Point Reel/ra   - MM: 10.00
Bed, Baths, SqFt Days Listed: 91
Commercial - Active - Waterfront Yes
Side of Island: Ocean - n/a

Pre- Construction price. Key West Prime oceanfront, fully enclosed boat and RV storage facility. 14w x 41L 17 H, door height 124x128, with 270 feet of oceanfront across Shark Key. Direct boat ramp access. 4ft MLW. Each Condo is equipped with individual electric meter and fire sprinklers systems. There is onsite parking, 100ft pier, water access, and restrooms for your convenience. Enjoy 24-hour access to your very own gated and secure recreational condominium. Finding storage space for your toys in the Florida Keys can be a costly endeavor. These enclosed storage condominiums provide immediate access to a secure space to protect your belongings from the harsh tropical climate. Ensuring your boat, RV, or whatever you enjoy, remains in top condition. You can enjoy the beautiful views as your boat is prepared and launched from the private boat ramp. Do you like waking up extra early to fight your way to a spot at the ramp? Secure your spot in one of our exclusive storage condominiums today to avoid the long lines at local ramps and start enjoying your time on the water without delays every weekend. With minimal units available, dont wait! Make the most of your boating experience in Key West. Experience convenience, security, and peace of mind for your toys!! -Avoid rental increases and lease hassles- Eliminate monthly rental payments-Add an asset to your financial portfolio- Perfect for long-term storage needs!

$525,000
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 718 SqFt Days Listed: 173
+10.53% ($50,000) 6 Price Changes : Last Change 76 Days Ago
Commercial - Active - Waterfront No
Side of Island: Median - n/a

Seize this rare opportunity to own a prime commercial condo in the heart of Old Town Key West. Situated on bustling Truman Avenue, this vibrant space is ideal for potential live work or establishing your business amongst a thriving mix of shops, restaurants, and historic landmarks. The condo boasts modern updates, including new flooring, fresh paint, and a renovated bathroom, providing a turnkey solution for your business needs. Embrace the island lifestyle and capitalize on the endless foot traffic - schedule your private viewing today!**HOA: $576/mo. includes building maintenance, insurance, and common area maintenance.

$550,000
Key West
Old Town Unrecord   - MM: 1.00
Bed, Baths, SqFt Days Listed: 295
-21.43% ($150,000) 1 Price Change : Last Change 104 Days Ago
Commercial - Contingent - Waterfront No
Side of Island: Median - n/a

Rare opportunity to purchase a transient/ ROGO license. The Transient/ROGO license is coming from a 6 bedroom unit. Buyer to verify transferability.

$560,000
Key West
Seafoam   - MM: 1.00
1 Bed, 1 Baths, 665 SqFt Days Listed: 53
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Boutique commercial, ground floor office condo for sale in Old Town at Seafoam Condominiums. Only one of two Commercial units in the building. This 665 sf. office is turnkey and perfect for Professionals looking for a small office to own vs. paying rent every month. Great location and close to everything in town either by walking or biking. Exterior has several large pane windows for natural light inside. To enter off the sidewalk there are a set of gorgeous, hand made mahogany french doors. Also, there is an interior side door for private access. Interior has 12 ceilings and the layout includes front seating area with a receptionist window, administrators office and private office in rear. Half bath is ADA compliant. This unit has been totally renovated and ready to move in. Renovations include new Brazilian cherry wood floors & keystone flooring in the bathroom. upgraded electric and lighting, freshly painted, Central AC and wireless Security system. Seafoam building has coded entrance, atrium hallways and large in-ground concrete pool exclusively for Condo owners and guests. HOA fee of $1,286/mos. includes insurances and reserves. Includes Liability, Wind and Flood insurance. Building has never flooded and in X flood zone. Building is up to date with SIRS and milestone inspections. Additional $587/mos. special assessment for windstorm insurance. Same owner since 2008.

The information being provided by the Florida Keys MLS is exclusively for consumers' personal, non-commercial use, and it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed accurate by the MLS. Data last updated on 06-16-2025.
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